Listen each group of people have the innate right to determine how they are viewed in whatever media form. If Spanish speaking people of European descent didn't make a fuss about a white guy of European descent gunning down a town full of their people then that is on them.

I think that Resident Evil 5 is indication of what happens when there are few black people in the game industry and in the decision making process. The fact that no one from the developmental stage to now even thought that having a white male run around shooting black Africans zombie or not might have some problematic connotations especially if they plan to heavily market and sell the game in the US shows an utter lack of sensitivity and complete naivete to not even ask the question and have a discussion.

Oh, and playing the 'what if' game and switching around races is a moot point because the racial history and dynamic between races are not the same.