Sounds familiar yet? Yup, we could be talking about the HIV/AIDS crisis, which has killed 15 million Africans, and infected 25 million others on the continent. Especially since one of the few sentences spoken in the Resident Evil 5 trailer is, “Casualties continue to mount over the long years I have struggled.”

Or maybe we’re reminded of the "one drop rule," concocted by racists who feared miscegenation in the era of slavery and Jim Crow to create a definition of whiteness. Is that what’s lurking behind the premise of this game?